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Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and ... - Science Advances

Engineering human megakaryocytic microparticles for targeted delivery of nucleic acids to hematopoietic stem and ...
Science Advances
Hematopoietic stem and progenitor cells (HSPCs) are important target cells for gene therapy applications. Current genetic modifications of HSPCs rely on viral vectors in vivo or electroporation ex vivo. Here, we developed a nonviral system based on ...

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