Nature.com | SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture Nature.com Centrioles are critical for the formation of centrosomes, cilia and flagella in eukaryotes. They are thought to assemble around a nine-fold symmetric cartwheel structure established by SAS-6 proteins. Here, we have engineered Chlamydomonas reinhardtii ... |